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Updated: Feb 10, 2026

Isolating Malignant and Non-Malignant B Cells from lck:eGFP Zebrafish
Published on: February 22, 2019
Early experience with cytoreduction and hyperthermic intraperitoneal chemotherapy at a newly developed center for
Whitney L Guerrero1, Gitonga Munene2, Paxton V Dickson1
1Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA.
Background:
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) has improved outcomes for patients with peritoneal carcinomatosis (PC). We present our experience from a newly developed peritoneal surface malignancy program.
Methods:
An IRB approved retrospective review was performed for the first 50 patients treated with CRS/HIPEC with clinicopathologic data described.
Results:
Patients treated with CRS/HIPEC were Caucasian (64%), female (66%) with a median age of 53 years (range, 11-73 years). Primary pathology included: appendix (40%, n=20), ovary (20%, n=10), colon (14%, n=7), desmoplastic small round cell tumor (14%, n=7) or other (12%, n=6). The median peritoneal cancer index (PCI) score was 15.5 (range, 1-39) and 92% underwent complete cytoreduction (CCR 0/1). Median hospital length of stay was 9.0 days (range, 6-35 days). Eight patients (16%) suffered major morbidity with 2 (4%) 30-day mortalities.
Conclusions:
Short-term outcomes observed after CRS/HIPEC in a newly developed center for PC are consistent with published higher volume center experiences.
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