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SAPHO Syndrome Masquerading as Metastatic Breast Cancer
Devin Malik1, Richa Handa2, Andrew Petraszko3
1Department of Hematology Oncology, Henry Ford Hospital, 2799 W. Grand Blvd., Detroit, MI 48202, USA.
Abstract:
SAPHO syndrome is a rare clinical entity composed of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO). We describe a case of SAPHO syndrome masquerading as metastatic breast cancer in a patient with localized breast cancer who presented with cord compression. There was no pathologic evidence of metastatic cancer; however, a bone scan indicated osseous involvement. After multidisciplinary review of images and with additional findings of pustulosis and acne, a clinical diagnosis of SAPHO was made.
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