Dilated cardiomyopathy and severe heart failure. An update for pediatricians

Paola Caviedes Bottner1, Tamara Córdova Fernández2, Marcos Larraín Valenzuela3

  • 1Unidad de Paciente Crítico Pediátrica, Hospital El Carmen de Maipú, Santiago, Chile.

Insights

Dilated cardiomyopathy, a primary cause of heart failure, requires comprehensive multidisciplinary management in children. Pediatricians play a key role in managing symptoms, preventing progression, and improving outcomes for affected children.

Area of Science:

  • Pediatric Cardiology
  • Heart Failure Research
  • Multidisciplinary Care Models

Background:

  • Dilated cardiomyopathy is a leading cause of heart failure and a common indication for heart transplantation in children.
  • Prognosis in pediatric dilated cardiomyopathy is influenced by etiology, age at onset, and disease severity.
  • Effective management necessitates addressing comorbidities and preventing complications to enhance patient status and prognosis.

Purpose of the Study:

  • To provide a review focused on the multidisciplinary management of pediatric dilated cardiomyopathy.
  • To guide pediatricians in the comprehensive care of children with this condition.
  • To highlight key considerations for optimizing outcomes in pediatric heart failure due to dilated cardiomyopathy.

Main Methods:

  • Literature review on pediatric dilated cardiomyopathy management.
  • Synthesis of current evidence regarding multidisciplinary approaches.
  • Guideline-oriented summary for clinical practice.

Main Results:

  • Dilated cardiomyopathy management requires a coordinated, multidisciplinary team approach.
  • Early identification and management of comorbidities are crucial.
  • Preventive strategies for complications significantly impact prognosis.

Conclusions:

  • Pediatricians should adopt a multidisciplinary strategy for managing dilated cardiomyopathy.
  • Comprehensive care improves the overall status and mitigates the prognosis of affected children.
  • Integrated management is essential for optimizing long-term outcomes in pediatric heart failure.

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
588
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
993
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
3.9K
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
947
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
391
Heart Failure Drugs: Diuretics01:22

Heart Failure Drugs: Diuretics

Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
1.0K