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Updated: Feb 10, 2026

Plaquing of Herpes Simplex Viruses
Published on: November 5, 2021
[Neonatal facial palsy: identification of herpes simplex virus 1 in cerebrospinal fluid. Case report]
Simón Lubián López1, Juan J Pérez Guerrero2, Patricia Salazar Oliva1
1Hospital Universitario Puerta del Mar. Cádiz, España.
Abstract:
Neonatal facial palsy is very uncommon and is generally diagnosed at birth. We present the first published case of neonatal facial palsy with identification of herpes simplex virus 1 in cerebrospinal fluid. A 35-day-old male was presented at the Emergency Department with mouth deviation to the left and impossibility of full closure of the right eye. There were no symptoms of infection or relevant medical history. Physical examination was compatible with peripheral facial palsy. Studies performed at admission were normal (blood count, biochemical analysis and coagulation blood tests and cerebrospinal fluid analysis). The patient was admitted on oral prednisolone and intravenous aciclovir. Cranial magnetic resonance was normal. Polymerase chain reaction test for herpes simplex virus 1 in cerebrospinal fluid was reported positive after 48 hours of admission. Patient followed good evolution and received prednisolone for 7 days and acyclovir for 21 days. At discharge, neurological examination was normal.
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