Related Experiment Video
Updated: Feb 10, 2026

Investigation of Beige Fat Biology and Metabolism Using the CRISPR SunTag-p65-HSF1 Activation System
Published on: January 6, 2023
Multifaceted Roles of Beige Fat in Energy Homeostasis Beyond UCP1
Carlos Henrique Sponton1,2,3, Shingo Kajimura1,2,3
1Diabetes Center, University of California, San Francisco, San Francisco, California.
Abstract:
Beige adipocytes are an inducible form of thermogenic adipose cells that emerge within the white adipose tissue in response to a variety of environmental stimuli, such as chronic cold acclimation. Similar to brown adipocytes that reside in brown adipose tissue depots, beige adipocytes are also thermogenic; however, beige adipocytes possess unique, distinguishing characteristics in their developmental regulation and biological function. This review highlights recent advances in our understanding of beige adipocytes, focusing on the diverse roles of beige fat in the regulation of energy homeostasis that are independent of the canonical thermogenic pathway via uncoupling protein 1.
More Related Videos
Related Concept Videos
Fats as Energy Storage Molecules
What is Homeostasis?
pH Homeostasis
Respiratory...
Activation Energy
Skeleton and Calcium Homeostasis
What is Energy?

