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Interobserver variation in CD30 immunohistochemistry interpretation; consequences for patient selection for targeted

Lianne Koens1, Peter M van de Ven2, Nathalie J Hijmering3

  • 1Department of Pathology, Academic Medical Center, Amsterdam, the Netherlands.

Histopathology
|May 15, 2018
PubMed
Summary

CD30 immunohistochemistry (IHC) staining shows poor reproducibility among pathologists, impacting patient selection for brentuximab vedotin treatment in clinical trials and daily practice. Improving CD30 scoring consistency is crucial for accurate lymphoma diagnosis and therapy. Keywords: CD30 IHC, lymphoma, brentuximab vedotin, reproducibility, patient selection.

Keywords:
CD30immunohistochemistryinterobserver variationmalignant lymphoma

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