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Updated: Feb 10, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Current Evidence-Based Understanding of the Epidemiology, Prevention, and Treatment of Atrial Fibrillation
Insights
Atrial fibrillation (AF) is a common heart rhythm disorder. This review summarizes current AF epidemiology, pathophysiology, and evolving treatment options for clinicians managing this growing patient population.
Area of Science:
- Cardiology
- Internal Medicine
- Epidemiology
Background:
- Atrial fibrillation (AF) is the most prevalent adult arrhythmia globally.
- The aging population increases the healthcare burden of AF.
- Evolving therapies address both AF treatment and stroke risk.
Purpose of the Study:
- To provide an updated, concise review of atrial fibrillation for clinicians.
- To summarize current epidemiology and pathophysiology of AF.
- To outline contemporary procedural therapeutic options for AF management.
Main Methods:
- Literature review of current epidemiology and pathophysiology.
- Summary of contemporary procedural therapeutic options.
- Focus on information relevant to internists and cardiologists.
Main Results:
- Comprehensive overview of AF epidemiology and pathophysiology.
- Detailed summary of current procedural treatment strategies.
- Emphasis on actionable information for frontline care providers.
Conclusions:
- Clinicians require updated knowledge on AF care options.
- Effective management of AF is crucial for an aging population.
- This review offers a valuable resource for delivering high-quality AF patient care.
Abstract:
Atrial fibrillation (AF) is the most common atrial arrhythmia in adults worldwide. As medical advancements continue to contribute to an ever-increasing aging population, the burden of atrial fibrillation on the modern health care system continues to increase. Therapies are also evolving, for treatment of the arrhythmia itself, and stroke risk mitigation. Internists and cardiologists alike are, in most instances, the frontline contact for AF patients, and would benefit from remaining facile in their understanding of care options. To continue to deliver high-quality care to this expanding patient group, an updated, concise review for the clinician is prudent. This article provides a comprehensive summary of the current epidemiology and pathophysiology of AF, as well as contemporary procedural therapeutic options.
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