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Seasonal blood pressure variation: implications for cardiovascular risk stratification
Pietro Amedeo Modesti1, Stefano Rapi2, Angela Rogolino2
1Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy. pamodesti@unifi.it.
Insights
Seasonal blood pressure variations impact cardiovascular risk. Low winter readings indicate true low risk, while summer lows may mask underlying winter risk, affecting patient and population assessments.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Long-term blood pressure (BP) variations are linked to cardiovascular events, particularly during colder seasons.
- Cardiovascular risk factors exhibit seasonal fluctuations, higher in winter and lower in summer.
- Seasonal BP changes can influence clinical trial and epidemiological survey outcomes.
Purpose of the Study:
- To highlight the impact of seasonal variations on cardiovascular risk assessment.
- To emphasize the need for personalized antihypertensive medication management.
- To guide the interpretation of BP readings in clinical practice and research.
Main Methods:
- Analysis of seasonal trends in blood pressure and cardiovascular risk factors.
- Evaluation of the influence of seasonal variations on risk stratification.
- Review of existing clinical trial and epidemiological data.
Main Results:
- Blood pressure and cardiovascular risk factors are significantly higher in winter than in summer.
- Low BP readings in summer may not reflect true low cardiovascular risk during winter.
- Seasonal variations can lead to misinterpretation of cardiovascular risk at both individual and population levels.
Conclusions:
- Seasonal variations in BP and risk factors necessitate careful consideration in clinical practice.
- Accurate cardiovascular risk assessment requires accounting for seasonal influences.
- Integrating seasonal data into risk models can improve patient management and research validity.
Abstract:
Long-term blood pressure variations contribute to an increased risk of cardiovascular events during cold season, requiring personalized management of antihypertensive medications in a single patient, and can influence the results of clinical trials and epidemiological surveys in population studies. In addition to blood pressure values, which guide the stratification of cardiovascular risk, other cardiovascular risk factor levels also tend to be higher in the winter months and lower in the summer months. The resultant estimation of individual cardiovascular risk may thus vary depending on the season. At the patient level, only a low value in the winter should thus be considered a true measure of low cardiovascular risk, whereas low values measured in the summer do not indicate a low risk in the winter. Likewise, estimations of cardiovascular risk in population studies may vary according to the period of the year. Efforts should thus be directed at considering the potential influence of seasonal variations in establishing "normal" and "high-risk" assessment at both the patient and population levels, integrating such data into clinical practice.
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