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Published on: November 19, 2020
Takotsubo Cardiomyopathy Mimicking Stent Thrombosis After Percutaneous Coronary Intervention
Furqan Khattak1, Muhammad Khalid1, Ghulam Murtaza1
1East Tennessee State University, Quillen College of Medicine, Johnson City, TN, USA.
Insights
Takotsubo cardiomyopathy, or "broken heart syndrome," mimics heart attack symptoms. This case highlights its diagnosis after initial treatment for coronary artery disease, emphasizing its distinct cardiac dysfunction.
Area of Science:
- Cardiology
- Cardiovascular Medicine
Background:
- Takotsubo cardiomyopathy (TTC) is a transient left ventricular dysfunction.
- It is often triggered by emotional or physical stress.
- TTC can mimic acute myocardial infarction on electrocardiogram (EKG).
Purpose of the Study:
- To present a case of Takotsubo cardiomyopathy.
- To illustrate diagnostic challenges in differentiating TTC from acute coronary syndrome.
- To highlight the importance of repeat angiography in ambiguous cases.
Main Methods:
- Case report of a 72-year-old woman.
- Initial presentation with ST-segment elevation myocardial infarction (STEMI) on EKG.
- Coronary angiography, percutaneous coronary intervention (PCI), and repeat emergent angiography.
Main Results:
- Initial angiography revealed coronary artery disease requiring PCI.
- Post-PCI, EKG changes resolved.
- Recurrent symptoms led to repeat angiography, showing patent stents and findings consistent with Takotsubo cardiomyopathy.
Conclusions:
- Takotsubo cardiomyopathy can present atypically, mimicking stent thrombosis.
- Coronary angiography is crucial for ruling out obstructive coronary artery disease and diagnosing TTC.
- Careful clinical evaluation and repeat angiography are vital for accurate diagnosis in complex cases.
Abstract:
Takotsubo cardiomyopathy, also known as "broken heart syndrome," is a transient left ventricular dysfunction associated with stress (usually emotional) induced myocardial injury and stunning. It often presents as myocardial infarction on surface electrocardiogram (EKG). Diagnosis is made by coronary angiography, which rules out coronary artery disease and shows pathognomonic apical ballooning. In this article, we present a case of a 72-year-old woman who initially presented with an ST segment elevation myocardial infarction on EKG. Coronary angiography showed severe left anterior descending artery and diagonal lesions requiring percutaneous coronary intervention. Post-percutaneous coronary intervention, EKG changes resolved. The next day, the patient developed recurrent chest pain and her EKG showed diffuse T-wave inversion in precordial leads with reemerging ST segment elevations concerning for stent thrombosis. The patient underwent repeat emergent coronary angiography, which showed patent stents and findings consistent with takotsubo cardiomyopathy.
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