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Is there a role for cardiac positron emission tomography in hypertrophic cardiomyopathy?

Paco E Bravo1,2,3

  • 1Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. paco.bravo@uphs.upenn.edu.

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
|May 16, 2018
PubMed

Insights

Coronary microvascular dysfunction is common in hypertrophic cardiomyopathy (HCM). Positron emission tomography (PET) can assess blood flow, aiding in evaluating heart failure and arrhythmias risk in HCM patients.

Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Coronary microvascular dysfunction and myocardial ischemia are prevalent in hypertrophic cardiomyopathy (HCM).
  • These conditions are implicated in the pathophysiology of heart failure and ventricular arrhythmias in HCM patients.

Purpose of the Study:

  • To review the literature on the role of positron emission tomography (PET) in evaluating HCM.
  • To explore future perspectives of PET in HCM patient assessment and risk stratification.

Main Methods:

  • Utilizes positron emission tomography (PET) for myocardial blood flow quantification.
  • Reviews existing literature on PET applications in hypertrophic cardiomyopathy.

Main Results:

  • PET offers a unique method to assess coronary microcirculation integrity and function in HCM.
  • PET can aid in understanding the contribution of microvascular dysfunction to HCM progression.

Conclusions:

  • PET is a valuable tool for evaluating coronary microvascular function in HCM.
  • PET has significant potential for risk stratification of HCM patients, guiding clinical management.

Keywords:
Basic scienceDiseases/processesModalitiesTests

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