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Related Experiment Video

Updated: Feb 10, 2026

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A Multi-Omics Database for Parasitic Nematodes and Trematodes.

John Martin1, Rahul Tyagi1, Bruce A Rosa1

  • 1McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.

Methods in Molecular Biology (Clifton, N.J.)
|May 16, 2018
PubMed
Summary

Helminth.net is a comprehensive web resource for nematode and trematode genomic data, offering tools to analyze species-omics properties and incorporating new datasets like gene expression and metagenomics.

Keywords:
BLASTDatabaseFunctional annotationGenome browserMetagenomeNematodesProteomeSearchTranscriptomeTrematodes

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Area of Science:

  • Parasitology
  • Bioinformatics
  • Genomics

Background:

  • Helminth.net originated as Nematode.net in 2000, focusing on nematode genome sequences.
  • It has expanded to include Trematode.net, covering both nematodes (roundworms) and trematodes (flatworms).

Purpose of the Study:

  • To describe the Helminth.net website, its integrated databases, and available analytical tools.
  • To highlight recent advancements in data inclusion, such as gene expression and population genomics.

Main Methods:

  • Hosting and investigating gene sequences from 73 nematode and 17 trematode species.
  • Developing tools for multifactorial querying of species-omics properties.
  • Integrating new datasets including gene/protein expression, population genomics, and metagenomics.

Main Results:

  • The resource now encompasses Nematode.net and Trematode.net, providing extensive genomic information.
  • Advanced tools allow for complex data analysis across multiple species and omics levels.
  • Recent updates include population genomics and cross-kingdom interaction data.

Conclusions:

  • Helminth.net serves as a vital, evolving platform for helminth genomic research.
  • The inclusion of diverse datasets enhances its utility for studying parasite biology and interactions.