Related Experiment Video
Updated: Feb 10, 2026

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation
Published on: October 25, 2024
Evaluation of the peritoneal surface disease severity score (PSDSS) in ovarian cancer patients undergoing
Roman Yarema1, Taras Fetsych1, Natalya Volodko1
1Department of Oncology and Medical Radiology, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
Background And Objectives:
Clinical experience suggests that cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) play an important role in the management of ovarian cancer. In order to improve patient selection, the peritoneal surface disease severity score (PSDSS) was previously introduced for use in colorectal cancer patients. However, almost no data exist regarding the utility of the PSDSS index in ovarian cancer patients.
Methods:
A retrospective study of the effectiveness of CRS and HIPEC was carried out in 59 patients with ovarian cancer. The PSDSS was based on three criteria: symptoms, extent of peritoneal dissemination, and primary tumor structure as assessed by histology and biomarker expression.
Results:
The overall survival time for patients with ovarian cancer in PSDSS Stage I was 48 ± 25.3 months. For PSDSS Stage II, the survival time was 26.5 ± 4.7 months. For PSDSS Stage III, it was 15.5 ± 4 months, and for PSDSS Stage IV, it was 6 ± 4.3 months. A multivariate analysis showed that the PSDSS stage was the only independent survival predictor.
Conclusions:
These data demonstrate that a PSDSS based on two pathogenetic types may be useful for predicting survival outcomes in ovarian cancer patients treated with CRS/HIPEC.
Related Concept Videos
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Types of Receptors: Cell Surface Receptors
Introduction to z Scores
z scores...
Introduction to z Scores
z scores...
z Scores and Area Under the Curve
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

