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Pharmaceutical Equivalents01:26

Pharmaceutical Equivalents

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As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
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Inhaled Medications01:23

Inhaled Medications

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Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
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Electron Carriers01:24

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Electron carriers can be thought of as electron shuttles. These compounds can easily accept electrons (i.e., be reduced) or lose them (i.e., be oxidized). They play an essential role in energy production because cellular respiration is contingent on the flow of electrons.
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Methods of Documentation I: Source-Oriented Records01:18

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Source-oriented records, or SOR, are medical record-keeping organized by the data source. The SOR system was first developed in the mid-1900s to organize the growing patient data in hospitals and other healthcare facilities.
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Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence01:22

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Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...
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Electron Affinity03:07

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The electron affinity (EA) is the energy change for adding an electron to a gaseous atom to form an anion (negative ion).
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TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
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The Electronic Pharmaceutical Record: A new method for medication reconciliation.

Camille Jurado1, Violaine Calmels1, Emilie Lobinet2

  • 1Department of Pharmacy, Hôpital Rangueil, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

Journal of Evaluation in Clinical Practice
|May 16, 2018
PubMed
Summary

The Electronic Pharmaceutical Record (ePR) aids hospital admission medication reconciliation (MedRec) by identifying regular medications, adherence, and self-medication. This tool is crucial for accurate patient medication lists.

Keywords:
clinical impactcontinuity of carehealth information technologymedication errormedication reconciliationpatient safety

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Area of Science:

  • Health Informatics
  • Clinical Pharmacy
  • Patient Safety

Background:

  • Accurate medication lists are vital for hospital admission medication reconciliation (MedRec).
  • Challenges in MedRec include data availability, reliability, and completeness.
  • The French Electronic Pharmaceutical Record (ePR) was developed for ambulatory patient medication safety.

Purpose of the Study:

  • To evaluate the suitability of the ePR as a tool for hospital admission MedRec.
  • To assess the clinical impact (CI) of data collected by the ePR during MedRec.

Main Methods:

  • A 6-month pilot study involving 249 MedRec files from a hospital diabetology department.
  • Supplementation of analysis with ePR data for relevant patients.
  • Evaluation of the ePR as a MedRec tool and its clinical impact.

Main Results:

  • The ePR contributed data for 28% of patients.
  • Discrepancies, often linked to polypharmacy, were identified.
  • Most frequent discrepancies included medication omission (72%), self-medication (8%), and non-adherence (9%).

Conclusions:

  • The ePR offers added value in MedRec by identifying regular medications, adherence, and self-medication.
  • The ePR is essential for comprehensive medication reconciliation.
  • Implementing the ePR can enhance patient safety during hospital admissions.