Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Insomnia01:27

Insomnia

496
Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
496
Management of Insomnia01:19

Management of Insomnia

682
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
682
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

324
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
324
Blind Procedures02:07

Blind Procedures

13.6K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
13.6K
Types of Hormones02:13

Types of Hormones

84.1K
Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells.
84.1K
The Placebo Effect01:54

The Placebo Effect

6.9K
The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
6.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Symptoms of Obsessive-Compulsive Disorder, Attention-Deficit/Hyperactivity Disorder, and Autism Spectrum Disorder in Children and Adolescents Attending a Headache Outpatient Clinic and School-Based Controls.

Journal of child neurology·2026
Same author

Executive Function Among Children and Adolescents With Primary Headache.

Journal of child neurology·2026
Same author

International Headache Week 2026: March 15-21.

The journal of headache and pain·2026
Same author

A cause for concern? How discrepancies between self- and parent proxy-reported quality of life are associated to well-being in children and adolescents attending a headache outpatient clinic: A case-control study.

Headache·2026
Same author

WHO's Global status report on neurology: mixed messages for people with headache disorders.

The journal of headache and pain·2026
Same author

The prevalence of headache disorders in children and adolescents in Nepal: a schools-based cross-sectional study.

The journal of headache and pain·2025

Related Experiment Video

Updated: Feb 10, 2026

Eye Tracking Young Children with Autism
09:03

Eye Tracking Young Children with Autism

Published on: March 27, 2012

46.6K

[Melatonin for children with insomnia].

Amalie Berring-Uldum1, Nanette Marinette Monique Debes, Charlotte Reinhardt Pedersen

  • 1helle.holst.01@regionh.dk.

Ugeskrift for Laeger
|May 16, 2018
PubMed
Summary
This summary is machine-generated.

Melatonin (MT) use for pediatric insomnia has increased, but evidence shows it only improves sleep latency, not duration. Good sleep hygiene effectively treats half of childhood sleep issues.

More Related Videos

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
04:34

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Published on: February 17, 2023

1.6K
Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)
09:05

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)

Published on: June 12, 2017

30.9K

Related Experiment Videos

Last Updated: Feb 10, 2026

Eye Tracking Young Children with Autism
09:03

Eye Tracking Young Children with Autism

Published on: March 27, 2012

46.6K
Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
04:34

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Published on: February 17, 2023

1.6K
Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)
09:05

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)

Published on: June 12, 2017

30.9K

Area of Science:

  • Pediatric Sleep Medicine
  • Pharmacology

Background:

  • Pediatric insomnia treatment with melatonin (MT) has doubled since 2011.
  • The efficacy and safety of MT in children (0-17 years) remain undetermined.
  • Concerns exist regarding MT's long-term effects on puberty.

Purpose of the Study:

  • To evaluate the clinical efficacy and safety of melatonin for pediatric insomnia.
  • To assess the impact of MT on sleep latency and total sleep time.
  • To review the role of sleep hygiene in treating childhood sleep problems.

Main Methods:

  • Analysis of recent clinical trials on melatonin for pediatric insomnia.
  • Review of long-term studies investigating MT's influence on puberty.
  • Assessment of adverse event reports associated with MT use.

Main Results:

  • Melatonin demonstrates a clinical effect on sleep latency but not on total sleep time.
  • Sleep hygiene interventions are effective in resolving sleep problems for 50% of children.
  • Safety evaluations often lack detailed adverse event reporting.

Conclusions:

  • Melatonin's efficacy in pediatric insomnia is limited to sleep latency.
  • Sleep hygiene is a primary, effective intervention for childhood sleep issues.
  • Further research is needed to establish MT's long-term safety profile in children.