Histomorphometric Comparison of 3 Osteotomy Techniques
Related Experiment Video
Updated: Feb 10, 2026

Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
Published on: May 6, 2020
Frederic B Slete1, Paul Olin2, Hari Prasad3
1Private Practice, Jackson, MI.
Purpose:
This pilot study compares the histomorphometric structure of osteotomy preparation through standard extraction drilling (SD), Summers osteotomes (SO), and a new method of nonextraction drilling called osseodensification (OD).
Method And Materials:
Fresh porcine tibia plateau was used as the surgical specimen. Three preparation methods (N = 6 for each) were used to prepare 18 osteotomies according to manufacturer protocols. Eighteen tapered screw-vent (4.7 × 13 mm) implants were placed. After osteotomy preparation and implant placement, all porcine tibias were placed in 10% formalin solution in preparation for histological staining and sectioning. Histomorphometric analysis of all samples was performed to compare immediate bone-to-implant contact (BIC) and the percentage of bone volume within a 2-mm zone surrounding the implant.
Results:
OD achieved 60.3% BIC, SO 40.7% BIC, and standard extraction drilling (SD) 16.3% BIC. The percentage of bone volume in the surrounding 2-mm width from the implant body using the same area units per sample was found to be greatest for OD.
Conclusion:
This study demonstrated that osteotomy preparation can influence both BIC and percentage of bone volume around the implant.
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