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Cholelithiasis and choledocholithiasis in children; risk factors for development
Barbora Frybova1, Jiri Drabek2, Jindra Lochmannova2
1Department of Pediatric Surgery, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.
Plos One
|May 16, 2018
Summary
Elevated body mass index (BMI) is linked to gallstones. Patients with choledocholithiasis, a condition involving bile duct stones, had higher BMI than those with simple gallstones.
Area of Science:
- Gastroenterology
- Pediatric Surgery
- Bariatric Medicine
Background:
- Gallstones, including cholelithiasis and choledocholithiasis, are common biliary tract conditions.
- Obesity, indicated by elevated body mass index (BMI), is a known risk factor for various health issues.
- Understanding the relationship between BMI and gallstone formation is crucial for preventative strategies.
Purpose of the Study:
- To investigate the association between body mass index (BMI) and the presence of gallstones.
- To compare anthropometric data in patients with simple cholelithiasis and choledocholithiasis versus a control group.
Main Methods:
- Retrospective review of 147 patients undergoing laparoscopic cholecystectomy (2001-2015).
- Comparison of BMI data from patients with gallstones against a control group and the general Czech pediatric population.
- Analysis included patients with simple cholelithiasis and choledocholithiasis.
Main Results:
- Patients with simple cholelithiasis exhibited significantly higher BMI than the control group and the standard Czech population.
- Patients with choledocholithiasis showed significantly higher BMI compared to both the general population and the control group.
- BMI was significantly higher in patients with choledocholithiasis than in those with simple cholelithiasis.
Conclusions:
- Elevated BMI is a significant risk factor for developing choledocholithiasis.
- The findings highlight the importance of weight management in gallstone prevention.
- Treatment outcomes for choledocholithiasis via ERCP and laparoscopic cholecystectomy are comparable to those for simple cholelithiasis.
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