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Updated: Feb 10, 2026

UV-Vis Spectroscopic Characterization of Nanomaterials in Aqueous Media
Published on: October 25, 2021
Use of continuous wavelet transform approach for simultaneous quantitative determination of multicomponent mixture by
Mahmoud Reza Sohrabi1, Vahid Mirzabeygi1, Mehran Davallo1
1Department of Chemistry, Faculty of Chemistry, Azad University, North Tehran Branch, P.O. Box 1913674711, Tehran, Iran.
Abstract:
In the present paper, a multicomponent analysis approach based on spectrophotometry method was developed for simultaneous determination of Guaifenesin (GU), Chlorpheniramine (CHL) and Pseudoephedrine (PSE) without any separation steps. The method under study is signal processing method based on Continuous Wavelet Transform (CWT) coupled with zero cross point technique. In this paper, CWT method was tested by synthetic ternary mixtures and was applied to the commercial cough syrup as a real sample and assessed by applying the standard addition technique. For demonstrate the accuracy of the results, other applications of signal processing, such as Derivative Transform (DT), Partial Least Squares (PLS) regression and Principal Components Regression (PCR) were used as comparative methods. Afterwards, the obtained results from analyzing the cough syrup by all methods were compared to the High-Performance Liquid Chromatography (HPLC) as a reference method. One-way analysis of variance test at 95% confidence level showed no significant differences between CWT and other applications.
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