Related Experiment Video
Updated: Feb 10, 2026
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Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics MSPP
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Re-thinking the chicken-Campylobacter jejuni interaction: a review
Wageha A Awad1,2, Claudia Hess1, Michael Hess1
1a Clinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health , University of Veterinary Medicine , Vienna , Austria.
Avian Pathology : Journal of the W.V.P.A
|May 17, 2018
Summary
Campylobacter jejuni is an infectious agent in chickens, not just a colonizer, impacting gut health, bird performance, and welfare. Further research is needed to understand its full effects and develop interventions.
Area of Science:
- Veterinary Microbiology
- Poultry Science
- Host-Pathogen Interactions
Background:
- Campylobacter jejuni (C. jejuni) is commonly found in chickens, traditionally viewed as a commensal.
- Recent evidence suggests C. jejuni actively interacts with the chicken gut epithelium, influencing host functions.
Purpose of the Study:
- To review current knowledge on the host-pathogen interaction between C. jejuni and chickens.
- To highlight gaps in understanding the infection cascade and its implications.
Main Methods:
- This review synthesizes findings from various experimental studies on C. jejuni in chickens.
- It examines host immune responses, gut integrity, microbiota alterations, and effects on bird performance.
Main Results:
- C. jejuni induces immune responses, damages intestinal epithelia, and alters gut microbiota composition.
- Infection impacts chicken performance, welfare, and movement patterns.
- Experimental parameters significantly influence study outcomes, necessitating standardization.
Conclusions:
- C. jejuni acts as an infectious agent in chickens, with significant consequences for host health and welfare.
- Understanding the full infection pathway is crucial for developing effective preventive strategies.
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