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Updated: Aug 16, 2026

Isolation and Characterization of Neutrophils with Anti-Tumor Properties
Published on: June 19, 2015
[The function of the neutrophil granulocyte in acne vulgaris]
R Vignale1, E Lasalvia, J Paciel
1Facultad de Medicina, Hospital de Clínicas Doctor Manuel Quintela, Montevideo, Uruguay.
Abstract:
Twenty seven patients with acne vulgaris were studied. Of them, 10 had minimal lesions and 17 had severe inflammatory lesions: nodulocystic, and conglobata. NBT and lysosomal neutrophil function was performed. The results shows a significative decreased values for the three test in patients with inflammatory lesions compared to patients with non-inflammatory lesions. The values for chemotactic function was 56.23 and 93%, for NBT test 50.82 and 93% and for lysosomal activity 60.88 and 88.9%, respectively. The authors proposed that the altered in vitro neutrophil function is a secondary phenomenon caused by specific and non-specific immunologic factors that occur in patients with severe inflammatory acne vulgaris.
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