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Middle-ear disease in children with cleft palate
Tulasi Kota Karanth1, Kenneth R Whittemore2
1Department of Otolaryngology & Communication Enhancement, Boston Children's Hospital, Boston, MA, United States.
This review details middle ear diseases in children with cleft palate (CP), covering epidemiology, pathogenesis, and management. Early screening and long-term follow-up are crucial for timely intervention and preventing complications like cholesteatoma.
Area of Science:
- Otolaryngology
- Pediatric Medicine
- Genetics
Background:
- Children with cleft palate (CP) exhibit a high prevalence of middle ear diseases.
- Anatomical abnormalities in CP contribute to the pathogenesis of otitis media with effusion and other middle ear conditions.
Purpose of the Study:
- To provide a comprehensive summary of middle ear diseases in pediatric patients with cleft palate.
- To review the epidemiology, pathogenesis, evaluation, management, and follow-up of middle ear disease in this population.
Main Methods:
- Systematic literature search of major databases including PubMed, Scopus, CINAHL, and Cochrane Library.
- Inclusion of English-language randomized control trials, meta-analyses, systematic reviews, and observational studies published up to July 2017.
Main Results:
- The review discusses the epidemiology and pathogenesis of middle ear diseases in children with CP.
- Detailed information is provided on evaluation methods, CP surgeries, potential complications, and recommended follow-up protocols.
Conclusions:
- Early detection of middle ear disease in infants with CP is essential, starting with newborn hearing screening.
- Regular tympanometry and otoscopy are vital for monitoring during follow-up visits.
- Ventilation tube insertion may be indicated, and long-term surveillance for cholesteatoma is recommended.
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