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Updated: Feb 10, 2026

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns
Published on: May 12, 2019
Visual Evoked Potential in Children With Developmental Disorders: Correlation With Neurodevelopmental Outcomes
JaYoung Kim1, In Young Sung1, Eun Jae Ko1
1Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Insights
Children with delayed visual evoked potential (VEP) results showed more developmental delays. VEP can indicate visual impairment and serve as an early sign for ophthalmologist consultation in children with developmental concerns.
Area of Science:
- Neuroscience
- Developmental Pediatrics
- Ophthalmology
Background:
- Developmental disorders in young children require accurate assessment.
- Visual evoked potential (VEP) is a tool to assess visual pathway function.
- Early identification of visual impairment is crucial for neurodevelopmental outcomes.
Purpose of the Study:
- To investigate neurodevelopmental outcomes in children with developmental disorders based on VEP results.
- To determine if VEP latency can predict developmental delays.
Main Methods:
- Retrospective analysis of 322 children under 42 months with developmental disability.
- Comparison of Bayley Scales of Infant and Toddler Development (BSID-II) scores between children with normal and delayed VEP latency.
- Mann-Whitney U-test used for statistical analysis.
Main Results:
- Children with delayed VEP latency exhibited significantly lower BSID-II index scores and developmental quotients.
- This difference was particularly pronounced in younger children (under 23 months).
- No significant differences in baseline characteristics were observed between groups.
Conclusions:
- Delayed VEP latency is associated with greater developmental delay in young children.
- VEP is a valuable, easily applicable tool for assessing children with suspected developmental delay and potential visual impairment.
- VEP results can prompt early ophthalmological consultation.
Objective:
To investigate the neurodevelopmental outcomes in children with developmental disorder according to visual evoked potential (VEP) results.
Methods:
We retrospectively analyzed children who visited our Department of Pediatric Rehabilitation Medicine with a chief complaint of developmental disability from January 2001 to July 2015. Of the 549 medical records reviewed, 322 children younger than 42 months who underwent both Bayley Scales of Infant and Toddler Development second edition (BSID-II) and VEP studies were enrolled. We compared the development of 182 children with normal VEP latency and 140 children with delayed VEP latency results using the BSID-II results. The Mann-Whitney U-test was used to analyze the differences between the two groups.
Results:
There were no significant differences in baseline characteristics between the two groups. The delayed VEP latency group showed a significant delay in BSID-II index scores and developmental quotients compared with the normal VEP latency group. In addition, a comparative analysis of developmental quotients of mental and psychomotor domains according to age (younger than 12 months, 12-23 months, and 24-42 months) revealed significantly lower values in children with delayed VEP latency compared to children with normal VEP latency, younger than 12 months and from 12 to 23 months.
Conclusion:
Children with delayed VEP latency showed more developmental delay than children with normal VEP latency. It is suggested that VEP can be easily applied to children with suspected developmental delay when physicians have concerns about visual impairment. Furthermore, it is proposed that VEP results could provide an insight into children's development and serve as early indicators for consultation with an ophthalmologist for the existing problem.
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