Related Experiment Video
Updated: Feb 10, 2026

Visualization of Candida albicans in the Murine Gastrointestinal Tract Using Fluorescent In Situ Hybridization
Published on: November 5, 2019
Similar and Distinct Mechanisms in the Protective Processes of Upper and Lower Gastrointestinal Tract
K Gyires1, Sz B Laszlo1, B Lazar1
1Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvarad ter 4., 1089 Budapest, Hungary.
Abstract:
Gastrointestinal (GI) mucosal integrity is based on the balance of aggressive and protective mechanisms. Mucosal damage may occur when the injurious factors become dominant or the mucosal defensive processes are impaired. The main target of the therapy against GI mucosal injury is the reduction of aggressive factors, however, the therapeutic possibilities for stimulation of mucosal defensive processes are rather limited. This overview focuses on the gastric and intestinal mucosal protective mechanisms and discusses the main targets that increase protective processes and increase the mucosal resistance to injurious stimuli at pre-epithelial, epithelial and sub-epithelial levels.
Related Concept Videos
Histology of the Gastrointestinal (GI) Tract
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
Anatomy of Respiratory System I: Upper Respiratory Tract
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
Anatomy of the Gastrointestinal System
Here's a detailed walkthrough of this complex system:
Reaction Mechanisms
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
Arteries of the Upper Limbs
Gastrointestinal Motility Disorders

