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Updated: Feb 10, 2026
08:40
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
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Use of Lactobacillus johnsonii in broilers challenged with Salmonella sofia
Chen G Olnood1, Sleman S M Beski1, Mingan Choct1,2
1School of Environmental and Rural Science, Armidale 2351, Australia.
Animal Nutrition (Zhongguo Xu Mu Shou Yi Xue Hui)
|May 17, 2018
Summary
The probiotic Lactobacillus johnsonii (L. johnsonii) improved broiler chicken health by reducing Salmonella sofia (S. sofia) and Clostridium perfringens in the gut. This enhanced gut microflora and colonization resistance in challenged birds.
Area of Science:
- Animal Science
- Microbiology
- Gut Health
Background:
- Salmonella sofia (S. sofia) infection negatively impacts broiler performance and gut health.
- Antimicrobial treatments are common but raise concerns about resistance.
- Probiotics offer a potential alternative for managing gut health in poultry.
Purpose of the Study:
- To evaluate the efficacy of Lactobacillus johnsonii (L. johnsonii) as a probiotic in broiler chickens challenged with Salmonella sofia (S. sofia).
- To assess the impact of L. johnsonii on gut microflora, bird performance, and intestinal development.
Main Methods:
- A 3x2 factorial design experiment with 288 Cobb broilers.
- Treatments included a negative control, a positive control with antimicrobials, and an L. johnsonii probiotic group.
- Birds were challenged with S. sofia at specific intervals, and L. johnsonii was administered via oral gavage.
Main Results:
- Salmonella sofia challenge significantly reduced bird performance and feed intake (P < 0.05).
- L. johnsonii administration reduced S. sofia and Clostridium perfringens counts in the gut.
- The probiotic enhanced colonization resistance against S. sofia challenge.
Conclusions:
- Lactobacillus johnsonii demonstrates potential as a novel probiotic for improving gut health and performance in broiler chickens.
- L. johnsonii can mitigate the negative effects of Salmonella sofia challenge by modulating gut microbiota.
- This study supports the use of L. johnsonii as a safe and effective alternative to antimicrobials in poultry production.
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