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Updated: Feb 10, 2026

Controlled Cervical Laceration Injury in Mice
Published on: May 9, 2013
Whiplash injury results in sustained impairments of cervical muscle function: A one-year prospective, controlled
1Spinal Cord Injury Center of Western Denmark, Viborg Regional Hospital, DK-8800 Viborg, Denmark.
Objective:
To investigate the temporal development of neck muscle function following whiplash injuries.
Design:
A 1-year prospective, controlled observational study.
Subjects:
A total of 141 individuals exposed to whiplash injury due to rear-end vehicle collisions and 40 age- and sex-matched controls with acute ankle distortion.
Methods:
Neck muscle strength and endurance during cervical flexion and extension were measured at 1 week, 1 month, 3 months, 6 months and 1 year after injury.
Results:
Notable reductions (23-30%) of neck strength in both directions were seen for whiplash-exposed subjects at all time points, compared with controls. Also, extensor endurance was reduced at 1 week, 1 month, 3 months, 6 months* and 1 year* (*non-significant). Within the whiplash group, non-recovered individuals (individuals who had not returned to pre-injury work capacity at one year) displayed ~50% reductions in cervical strength in both directions at all time points, compared with recovered whiplash individuals.
Conclusion:
Cervical muscular functioning is impaired for at least one year after whiplash injury, well beyond the time course of recovery of neck mobility and pain sensations. In whiplash-exposed individuals, non-recovery is associated with considerable muscular weakness. There is a need for increased clinical focus on early neck function after whiplash injury.
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