Related Experiment Video
Updated: Feb 10, 2026
04:05
Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse
Published on: October 6, 2023
780
Thyroid hormones and female reproduction
Juneo F Silva1, Natália M Ocarino2, Rogéria Serakides2
1Centro de Microscopia Eletrônica, Departamento de Ciências Biológicas, Universidade Estadual de Santa Cruz, Ilhéus, Bahia, Brazil.
Biology of Reproduction
|May 17, 2018
Summary
Thyroid hormones are crucial for female reproduction, impacting ovarian, uterine, and placental health. Thyroid dysfunction (hypo- or hyperthyroidism) can lead to infertility and adverse pregnancy outcomes in women and animals.
Area of Science:
- Reproductive Endocrinology
- Endocrinology
- Gynecology
Background:
- Thyroid hormones regulate metabolism and development of key reproductive tissues, including ovaries, uterus, and placenta.
- Maternal thyroid dysfunction is linked to various reproductive issues such as infertility, irregular cycles, anovulation, and pregnancy complications.
Purpose of the Study:
- To review and synthesize current knowledge on thyroid hormone roles in female reproductive morphophysiology.
- To examine the impact of hypothyroidism and hyperthyroidism on reproductive function in women and animals.
Main Methods:
- Literature review of prospective and retrospective studies in women.
- Analysis of in vivo and in vitro experimental assays using animal models and cell cultures.
Main Results:
- Thyroid hormones are essential for normal ovarian, uterine, and placental function.
- Hypothyroidism and hyperthyroidism significantly disrupt female reproductive processes and outcomes.
Conclusions:
- Understanding thyroid hormone regulation of reproduction is vital for addressing infertility and reproductive disorders.
- This review consolidates information to improve therapeutic strategies for thyroid-related reproductive dysfunction.
More Related Videos
Related Concept Videos
01:24Disorders of the Female Reproductive System
4.5K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
4.5K
01:18Functions of Thyroid Hormones
5.7K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
5.7K
02:13Types of Hormones
84.1K
Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells.
84.1K
01:20Synthesis and Regulation of Thyroid Hormones
8.0K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
8.0K
01:27Reproductive Cloning
32.8K
Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic...
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic...
32.8K
01:33Hormonal Regulation
36.2K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
36.2K