Antibacterial, anticancer and antioxidant potential of silver nanoparticles engineered using Trigonella
Shivangi Goyal1, Nidhi Gupta1, Ajeet Kumar2
1Department of Biotechnology, The IIS University, Gurukul Marg, SFS, Mansarovar, Jaipur 302020 Rajasthan, India.
Abstract:
In this study, the authors report a simple and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) using Trigonella foenum-graecum (TFG) seed extract. They explored several parameters dictating the biosynthesis of TFG-AgNPs such as reaction time, temperature, concentration of AgNO3, and TFG extract amount. Physicochemical characterisation of TFG-AgNPs was done on dynamic light scattering (DLS), field emission electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy. The size determination studies using DLS revealed of TFG-AgNPs size between 95 and 110 nm. The antibacterial activity was studied against Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa and Staphylococcus aureus The biosynthesised TFG-AgNPs showed remarkable anticancer efficacy against skin cancer cell line, A431 and also exhibited significant antioxidant efficacy.
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