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Updated: Feb 10, 2026

Live Imaging of the Ependymal Cilia in the Lateral Ventricles of the Mouse Brain
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Published on: June 1, 2015

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Infantile medulloepithelioma in the lateral ventricle and cerebellopontine angle: Two case reports

Qiang Li1, Ni Chen, Yan Ju

  • 1Department of Neurosurgery Department of Pathology, West China Hospital of Sichuan University.

Medicine
|May 17, 2018
PubMed
Abstract

Insights

Intracranial medulloepitheliomas are rare, malignant brain tumors. Surgical resection may prolong survival, but aggressive treatments offer poor prognosis, necessitating further research for better outcomes.

Area of Science:

  • Neuro-oncology
  • Pediatric Neurosurgery

Background:

  • Intracranial medulloepitheliomas are exceptionally rare and highly malignant central nervous system tumors.
  • Intraventricular medulloepitheliomas are seldom reported, with limited understanding of their clinical characteristics.

Observation:

  • This report details two pediatric cases of intracranial medulloepithelioma.
  • Case 1: A one-month-old boy with a tumor in the right lateral ventricle, a previously undocumented location.
  • Case 2: An eleven-month-old girl with a tumor in the right cerebellopontine angle.

Findings:

  • Both patients underwent complete surgical resection via craniotomy.
  • The infant boy survived for 3 months post-operation with chemotherapy.
  • The infant girl succumbed 6 months post-operation despite intensive adjuvant chemotherapy.

Implications:

  • Complete surgical resection appears to be a safe and effective method for extending patient survival.
  • The overall prognosis for medulloepithelioma remains poor, underscoring the urgent need for novel therapeutic strategies.
  • Further research is critical to enhance treatment efficacy for this rare pediatric brain tumor.

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