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Updated: Feb 10, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

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Are left ventricular ejection fraction and left atrial diameter related to atrial fibrillation recurrence after

Xiao Jin1, Jianke Pan, Huanlin Wu

  • 1Second School of Clinical Medicine, Guangzhou Univ Chinese Med Department of Orthopedics, Second Affiliated Hospital of Guangzhou Univ Chinese Med (Guangdong Provincial Hospital of Chinese Medicine) Beijing University of Chinese Medicine, Beijing, China Department of Cardiology, Second Affiliated Hospital of Guangzhou Univ Chinese Med (Guangdong Provincial Hospital of Chinese Medicine).

Medicine
|May 17, 2018
PubMed

Insights

Elevated left atrial diameter is linked to atrial fibrillation recurrence after catheter ablation. Left ventricular ejection fraction does not significantly impact recurrence in most cases. Further research is needed.

Area of Science:

  • Cardiology
  • Medical Research

Background:

  • Atrial fibrillation (AF) is a common arrhythmia, with catheter ablation as a primary treatment.
  • AF recurrence post-ablation is frequent, necessitating investigation into predictive factors.
  • Previous studies lack consensus on the impact of LVEF and LA diameter on AF recurrence.

Purpose of the Study:

  • To determine if left ventricular ejection fraction (LVEF) and left atrial diameter (LA diameter) influence AF recurrence after catheter ablation.
  • To synthesize existing evidence through a meta-analysis.

Main Methods:

  • A meta-analysis was conducted using data from PubMed, Embase, and Cochrane Library up to September 2017.
  • Thirteen studies comprising 2825 patients were included.
  • RevMan 5.3.5 software was utilized for the analysis.

Main Results:

  • Elevated LA diameter was significantly associated with increased AF recurrence (MD=2.19, P<.001).
  • Baseline LVEF showed no significant association with AF recurrence (MD=-0.91, P=.14).

Conclusions:

  • Increased LA diameter may predict AF recurrence post-catheter ablation.
  • LVEF does not appear to be a significant predictor of recurrence when normal or mildly decreased.
  • Publication bias necessitates further investigation into AF recurrence mechanisms.

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