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Paediatric type 1 diabetes 2018: Clinical and research insights
Stephen J Zborovski1, Farid H Mahmud1
1Division of Endocrinology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, Ontario.
Insights
Advances in type 1 diabetes management for youth include new insulin formulations and technologies. Innovations like insulin pumps and continuous glucose monitoring improve glycemic control and quality of life.
Area of Science:
- Pediatrics
- Endocrinology
- Diabetes Technology
Background:
- Type 1 diabetes management in children and adolescents faces challenges due to glucose variability.
- Insulin selection and lipohypertrophy significantly impact blood glucose levels.
- Continuous advancements in clinical practice and technology are transforming diabetes care.
Purpose of the Study:
- To provide clinicians with an overview of recent innovations in pediatric type 1 diabetes care.
- To highlight the impact of new technologies on glycemic control and quality of life.
- To discuss advancements in insulin therapy and glucose monitoring systems.
Main Methods:
- Review of current literature on pediatric type 1 diabetes management.
- Analysis of emerging clinical and technological innovations.
- Discussion of new insulin analogues, insulin pumps, and continuous glucose monitoring (CGM) systems.
Main Results:
- New insulin analogues and advanced insulin pumps offer improved therapeutic options.
- Continuous glucose monitoring systems are increasingly integrated into diabetes management, reducing the need for capillary blood glucose checks.
- Features like 'low glucose suspend' represent steps toward fully automated insulin delivery systems.
Conclusions:
- Technological innovations are significantly enhancing the management of type 1 diabetes in pediatric populations.
- Future developments aim for fully closed-loop systems to further optimize glycemic control and patient well-being.
- Clinicians need to stay updated on these evolving aspects of diabetes care for children and adolescents.
Abstract:
The management of children and adolescents with type 1 diabetes continues to progress as clinical and technological innovations enter into practice. Variability in glucose readings can present a significant challenge for care providers, patients and families alike and recent research demonstrates that insulin selection and site-related lipohypertrophy can significantly influence blood glucose levels. New technology aims to improve both glycemic control and quality of life. New insulin analogues have been developed and insulin pumps and continuous glucose monitoring systems continue to evolve toward a fully closed-loop system. While such systems are not yet currently available, incremental features such as 'low glucose suspend' are offered. As well, glucose sensors are now available that can be used for insulin dosing while reducing the number of capillary blood sugar checks. This review aims to provide the clinician with an overview of some of these latest aspects of diabetes care for children and adolescents.
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