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The Canadian Immunization Monitoring Program, ACTive (IMPACT): Active surveillance for vaccine adverse events and

J A Bettinger1, S A Halperin2, W Vaudry3

  • 1Vaccine Evaluation Center, BC Children's Hospital and the University of British Columbia, Vancouver, BC.

Canada Communicable Disease Report = Releve Des Maladies Transmissibles Au Canada
|May 18, 2018
PubMed

Insights

The Canadian Immunization Monitoring Program, ACTive (IMPACT) has monitored severe adverse events following immunization (AEFIs) and childhood diseases for 25 years. This active surveillance network enhances vigilance for serious AEFIs in children across Canada.

Area of Science:

  • Pediatric Infectious Diseases
  • Public Health Surveillance
  • Immunization Safety

Background:

  • The Canadian Immunization Monitoring Program, ACTive (IMPACT) has operated for nearly 25 years.
  • It focuses on active surveillance of severe adverse events following immunization (AEFIs) and vaccine-preventable diseases in children.
  • IMPACT is a key part of Canada's national AEFI monitoring system.

Purpose of the Study:

  • To describe the structure and function of the IMPACT network.
  • To highlight its role in monitoring vaccine safety and effectiveness in pediatric populations.
  • To emphasize the importance of active surveillance for detecting severe AEFIs.

Main Methods:

  • Utilizes a network of volunteer pediatric infectious diseases investigators across 12 tertiary care children's hospitals.
  • Employs dedicated nurses at each site for systematic searching and reporting of potential AEFIs.
  • Reports data to local, provincial, and national public health authorities.

Main Results:

  • Demonstrates a sustained, long-term commitment to monitoring pediatric immunization safety.
  • Highlights the effectiveness of active surveillance in identifying severe AEFIs.
  • Provides a robust framework for tracking vaccine-preventable diseases.

Conclusions:

  • The IMPACT network provides essential, vigilant surveillance of severe AEFIs in Canadian children.
  • Active surveillance is crucial for maintaining public trust and ensuring vaccine safety.
  • The program's longevity underscores its value in pediatric public health.

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