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CATMAT statement on disseminated strongyloidiasis: Prevention, assessment and management guidelines
A K Boggild1,2,3, M Libman4, C Greenaway5
1Tropical Disease Unit, Toronto General Hospital, University Health Network, Toronto, ON.
Summary
Screening for strongyloidiasis is recommended for at-risk individuals, especially those with specific risk factors like immunosuppression or HTLV-1 infection. Early diagnosis and management are crucial to prevent fatal disseminated strongyloidiasis.
Area of Science:
- Medical Parasitology
- Infectious Diseases
- Clinical Medicine
Background:
- Strongyloides stercoralis is a human parasite prevalent in tropical/sub-tropical regions.
- Untreated infections can lead to fatal disseminated strongyloidiasis.
Purpose of the Study:
- To provide clinical guidance on preventing, assessing, and managing disseminated strongyloidiasis.
- To offer a practical tool for clinicians in Canada.
Main Methods:
- A comprehensive literature review was conducted.
- Evidence was evaluated from systematic reviews, case reports, and guidelines.
- A working group from the Committee to Advise on Tropical Medicine and Travel (CATMAT) developed the statement.
Main Results:
- Screening for strongyloidiasis is advised for individuals with epidemiologic risk or comorbidities.
- Highest risk individuals include those from endemic areas undergoing immunosuppression or with HTLV-1 infection.
- Diagnosis relies on serologic testing and larval detection in specimens.
Conclusions:
- Strongyloidiasis is common in global migrant populations; screening requires individual risk assessment.
- Referral to tropical medicine specialists is recommended for suspected/confirmed cases.
- A diagnostic and treatment algorithm is available as a reference tool.
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