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Updated: Feb 10, 2026

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Published on: May 31, 2021
[The prevalence of allergy-related symptoms and their risk factorinvestigation in early life]
1Department of Otolaryngology Head and Neck Surgry,the Second People's Hospital of Wuhu,Wuhu,241000,China.
Insights
Lactation eczema and house dust mite sensitization are key risk factors for developing respiratory issues in young children. Allergic respiratory symptoms often begin with rhinitis in this age group.
Area of Science:
- Pediatric Allergy and Immunology
- Environmental Health
- Epidemiology
Background:
- Allergy-related symptoms are common in early childhood.
- Identifying early risk factors is crucial for preventing chronic respiratory diseases.
Purpose of the Study:
- To investigate the incidence of allergy-related symptoms in preschool children.
- To identify associated risk factors, including history of eczema, wheezing, and sensitization to house dust mites.
Main Methods:
- A cohort of 205 children aged 3-4 years participated.
- Symptom questionnaires and serum IgE testing for house dust mites were administered.
- Logistic regression analysis was used to determine risk factors.
Main Results:
- History of lactation eczema (OR 2.76) and wheezing (OR 2.40) were significant risk factors for rhinitis.
- House dust mite sensitization (24% prevalence) was also a risk factor for rhinitis (OR 2.10).
- No association was found between house dust mite sensitization and wheezing.
Conclusions:
- Lactation eczema and house dust mite sensitization are significant risk factors for early childhood respiratory diseases.
- Rhinitis symptoms appear to be an early indicator of house dust mite allergy.
Abstract:
Objective:The aim of this study is to investigate the incidence of allergy-related symptoms and the associated risk factors.Method:There were 205 children aged 3 to 4 years old recruited for this study.Questionnaires on skin,wheezing and rhinitis symptoms were answered,and total IgE and specific IgE in serum against house dust mite extracts were tested.Logistic regression analysis with which we calculated odds ratio(OR) and 95% confidence interval(95%CI) were used for risk factor analysis.Result:Questionnaire results show that the reported history of symptoms was 43%(88 cases) for lactation eczema and 25%(51 cases) for wheezing.The currently reported symptoms was 19%(38 cases) for frequent skin rashes,16% (33 cases) for frequent wheezing and 46%(95 cases) for rhinitis symptoms.There are 33% (68 cases) of the children reported with no symptoms currently.The lactation eczema history(OR[95%CI]:2.76[1.10-3.40],P<0.05)and wheezing history(OR[95%CI]:2.40[1.22-4.73],P<0.01)are both the risk factors for developing rhinitis symptoms.Serology test shows that house dust mite IgE prevalence is 24%,which is the risk factor developing rhinitis symptom(OR[95%CI]:2.10[1.09-4.07],P<0.05).But it has nothing to do with wheezing symptom.Conclusion:Lactation eczema and house dust mite sensitization are the risk factors for developing respiratory diseases in early childhood.The house dust mite allergic respiratory symptom starts with rhinitis symptom.
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