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Updated: Feb 10, 2026

The Use of Chemostats in Microbial Systems Biology
Published on: October 14, 2013
New Techniques for the Generation and Analysis of Tailored Microbial Systems on Surfaces
Ariel L Furst1, Matthew J Smith1, Matthew B Francis1,2
1Department of Chemistry , University of California, Berkeley , Berkeley , California 94720-1460 , United States.
Abstract:
The interactions between microbes and surfaces provide critically important cues that control the behavior and growth of the cells. As our understanding of complex microbial communities improves, there is a growing need for experimental tools that can establish and control the spatial arrangements of these cells in a range of contexts. Recent improvements in methods to attach bacteria and yeast to nonbiological substrates, combined with an expanding set of techniques available to study these cells, position this field for many new discoveries. Improving methods for controlling the immobilization of bacteria provides powerful experimental tools for testing hypotheses regarding microbiome interactions, studying the transfer of nutrients between bacterial species, and developing microbial communities for green energy production and pollution remediation.
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