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Beta-endorphin-like immunoreactivity increases in cerebrospinal fluid of acute head-injured patients
1Department of Neurosurgery, Chang Zheng Hospital, Second Military Medical College, Shanghai, People's Republic of China.
Neuropeptides
|October 1, 1988
Abstract:
beta-endorphin-like immunoreactivity (beta-ELI) was measured in cerebrospinal fluid (CSF) of 36 acute head-injured patients and 12 patients without head injury as controls. The mean level of beta-ELI in CSF of controls, mild cerebral contusions, and severe cerebral contusion patients were 51.9 +/- 5.6 pg/ml, 110.5 +/- 14.5 pg/ml, and 173.8 +/- 20.1 pg/ml respectively, with significant difference between them. The results also showed that beta-ELI may reflect the prognosis of acute head-injured patients.