Hemodialysis Catheter-Related Central Venous Thrombosis: Clinical Approach to Evaluation and Management

Nalaka Gunawansa1, Dinesha Himali Sudusinghe2, Dilushi Rowena Wijayaratne3

  • 1National Institute of Nephrology Dialysis and Transplantation, National Hospital of Sri Lanka, Colombo, Sri Lanka; University of Liverpool, Liverpool, United Kingdom.

Insights

Central venous catheters (CVCs) in hemodialysis can cause thrombosis, leading to dysfunction and limb morbidity. Minimizing CVC use and vigilant monitoring are key to preventing these complications.

Area of Science:

  • Nephrology
  • Vascular Surgery
  • Critical Care Medicine

Background:

  • Central venous catheters (CVCs) are frequently utilized for hemodialysis access.
  • Catheter-related vascular thrombosis is a common and serious complication of CVC use.
  • This complication leads to catheter dysfunction, potential loss of vascular access, and significant limb morbidity.

Purpose of the Study:

  • To highlight the challenges in managing catheter-related thrombi in hemodialysis patients.
  • To emphasize the lack of evidence-based guidelines for treatment.
  • To advocate for preventative strategies regarding CVC use.

Main Methods:

  • Review of existing literature on CVC-related thrombosis in hemodialysis.
  • Analysis of clinical implications and management challenges.
  • Discussion of preventative measures and surveillance strategies.

Main Results:

  • Catheter-related thrombosis frequently causes CVC dysfunction and loss of vascular access.
  • Limited evidence-based guidelines exist, complicating clinical management.
  • Preventative strategies are crucial for mitigating morbidity.

Conclusions:

  • Minimizing the use of CVCs in hemodialysis is the primary strategy for prevention.
  • Careful planning, meticulous catheter care, and early complication surveillance are essential when CVCs are unavoidable.
  • Proactive management can significantly reduce associated patient morbidity.

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