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Adjunctive electroconvulsive therapy for schizophrenia.

P S Das1, S Saxena1, D Mohan1

  • 1Department of Psychiatry, All Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.

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|May 19, 2018
PubMed
Summary
This summary is machine-generated.

Electroconvulsive therapy (ECT) can be an effective add-on treatment for Indian schizophrenia patients who do not respond well to medication alone. This study found significant improvements in functioning for patients receiving ECT alongside drugs.

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Area of Science:

  • Psychiatry
  • Neurology

Background:

  • The efficacy of electroconvulsive therapy (ECT) in schizophrenia treatment remains debated.
  • Indian patients often present with late-stage schizophrenia, complicating treatment approaches.

Purpose of the Study:

  • To evaluate the effectiveness of electroconvulsive therapy (ECT) as an adjunctive treatment in Indian schizophrenia patients.
  • To assess ECT's role in patients with chronic schizophrenia or those unsuitable for pharmacotherapy alone.

Main Methods:

  • A study involving 48 schizophrenia patients, with 30 diagnosed with chronic disease.
  • Patients were divided into two groups: 23 received medication only, while 25 received both medication and electroconvulsive therapy (ECT).
  • The Global Assessment Scale (GAS) was utilized to measure patient functioning and treatment response.

Main Results:

  • The Global Assessment Scale (GAS) scores at admission were 27±9.4 for the drugs-alone group and 19±8.4 for the drugs plus ECT group.
  • At discharge, both groups showed significant improvement, with scores rising to 57±16 and 62±14.3, respectively.
  • The addition of ECT to drug therapy showed promising results in improving patient functioning.

Conclusions:

  • Electroconvulsive therapy (ECT) demonstrates potential as a valuable adjunctive treatment for Indian schizophrenia patients.
  • ECT may be particularly beneficial for individuals with schizophrenia who are not candidates for drug therapy alone.
  • Further research into optimizing ECT protocols for this population is warranted.