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Updated: Jul 9, 2026

Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
Published on: August 7, 2017
Computational Convolution of SELDI Data for the Diagnosis of Alzheimer's Disease
Destiny E O Anyaiwe1, Gautam B Singh2, George D Wilson3
1Department of Mathematics and Computer Science, Lawrence Technological University, Southfield, MI 48075, USA. oanyaiwe@ltu.edu.
Abstract:
Alzheimer's disease is rapidly becoming an endemic for people over the age of 65. A vital path towards reversing this ominous trend is the building of reliable diagnostic devices for definite and early diagnoses in lieu of the longitudinal, usually inconclusive and non-generalize-able methods currently in use. In this article, we present a survey of methods for mining pools of mass spectrometer saliva data in relation to diagnosing Alzheimer's disease. The computational methods provides new approaches for appropriately gleaning latent information from mass spectra data. They improve traditional machine learning algorithms and are most fit for handling matrix data points including solving problems beyond protein identifications and biomarker discovery.
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