Related Experiment Videos
Radiological screening for atlanto-axial instability in Down's syndrome.
B Jagjivan1, P A Spencer, G Hosking
1Department of Radiology, Northern General Hospital, Sheffield, UK.
Clinical Radiology
|November 1, 1988
Summary
Screening for Down's syndrome patients revealed significant rates of cervical spine instability, particularly in those under 25. Early degenerative changes were also noted, highlighting risks for this population.
Area of Science:
- Orthopedics
- Radiology
- Genetics
Background:
- Down's syndrome is associated with an increased risk of atlanto-axial instability.
- Cervical spine abnormalities can lead to serious neurological complications.
Purpose of the Study:
- To screen Down's syndrome patients for atlanto-axial instability.
- To assess the prevalence of cervical spine degenerative changes in this population.
Main Methods:
- Cervical spine X-rays were performed on 220 patients with Down's syndrome.
- Measurements included the predental distance to identify instability.
- Radiographs were evaluated for degenerative changes.
Main Results:
- 6.8% of patients showed an abnormal predental distance.
- 1.8% exhibited atlanto-axial subluxation.
- 70% of abnormal findings were in patients under 25 years old.
- Early degenerative changes were observed, increasing with age.
Conclusions:
- Atlanto-axial instability is a significant concern in Down's syndrome patients, especially the young.
- The high incidence in the under-25 group suggests a need for targeted screening and precautions during physical activities.
- Progressive degenerative changes necessitate long-term monitoring.