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Draft Genome Sequence of New Vancomycin-Resistant Enterococcus faecium Sequence Type 1421

Kelvin W C Leong1, Louise A Cooley2, Ronan F O'Toole3,4

  • 1School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia.

Genome Announcements
|May 19, 2018
PubMed

Insights

Vancomycin-resistant Enterococcus faecium (VREfm) is a growing global health threat. This study reports the whole-genome sequence of a new VREfm strain, ST1421, identified in Tasmania.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • Vancomycin-resistant Enterococcus faecium (VREfm) poses a significant challenge to healthcare infection control globally.
  • A notable rise in VREfm isolation occurred in Tasmanian public hospitals in 2015.

Purpose of the Study:

  • To characterize a newly identified VREfm strain through whole-genome sequencing.
  • To provide genomic data for a novel VREfm sequence type.

Main Methods:

  • Draft whole-genome sequencing of VREfm isolates.
  • Bioinformatic analysis to determine sequence type.

Main Results:

  • The draft whole-genome sequence of a novel VREfm strain was obtained.
  • This strain was designated as a new sequence type, ST1421.

Conclusions:

  • The identification and sequencing of ST1421 contribute to understanding VREfm epidemiology.
  • Genomic data on novel VREfm strains are crucial for infection control strategies.

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