Related Experiment Video
Updated: Feb 10, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
[Optical coherence tomography for skin pathologies]
1Klinik für Dermatologie und Allergologie, Klinikum Augsburg, Sauerbruchstr. 6, 86179, Augsburg, Deutschland. julia.welzel@klinikum-augsburg.de.
Abstract:
Optical coherence tomography (OCT) has become established in routine diagnosis in dermatology only in the last few years. The reason is that the skin is a challenge for OCT as a strong scattering medium, because only a very small proportion of photons is reflected and can be used for imaging. In addition, in most cases a visual assessment or a biopsy is sufficient. Nevertheless, the main field of application in dermatology is the diagnostics of epithelial skin tumors. The OCT is suitable for the early recognition of small, clinically and light microscopically unspecific basal cell carcinomas as well as for the differential diagnosis of other tumors and precancerous lesions. Using OCT, the preoperative measurement of tumor spread, observation of the course and treatment control of non-surgical procedures are possible; therefore, in many cases a biopsy or treatment control can be avoided. Dynamic OCT is a newly developed add on technique to visualize and quantify the superficial blood vessels of the skin. First studies are focused on the evaluation of tumor vessels, wound healing and monitoring of laser therapy. In ophthalmology, OCT diagnostics of basal cell carcinomas on the eyelids as well as for planning and control of eyelid interventions can be of interest.
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
Sensory Functions of the Skin
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...

