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[Optical coherence tomography for skin pathologies].

J Welzel1, S Schuh2

  • 1Klinik für Dermatologie und Allergologie, Klinikum Augsburg, Sauerbruchstr. 6, 86179, Augsburg, Deutschland. julia.welzel@klinikum-augsburg.de.

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|May 19, 2018
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography (OCT) is now used in dermatology for diagnosing epithelial skin tumors, offering early detection and aiding in treatment decisions. This imaging technique helps avoid biopsies by assessing tumor spread and monitoring non-surgical treatments.

Keywords:
Basal cell carcinomaEpithelial neoplasmsEyelid neoplasmsNon-invasive diagnosticsTherapy control

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Area of Science:

  • Dermatology
  • Medical Imaging
  • Oncology

Background:

  • Optical coherence tomography (OCT) presents challenges in skin imaging due to high light scattering.
  • Traditional methods like visual assessment and biopsy are often sufficient in dermatology.
  • OCT's application in routine dermatological diagnosis is a recent development.

Purpose of the Study:

  • To highlight the diagnostic capabilities of OCT in dermatology, particularly for epithelial skin tumors.
  • To explore the potential of OCT in early tumor recognition and differential diagnosis.
  • To assess OCT's role in preoperative tumor assessment and treatment monitoring.

Main Methods:

  • Utilizing optical coherence tomography (OCT) for in vivo skin imaging.
  • Applying dynamic OCT to visualize and quantify superficial skin vasculature.
  • Comparing OCT findings with clinical presentation and histopathology.

Main Results:

  • OCT enables early detection of subtle basal cell carcinomas and aids in differentiating various skin tumors and precancerous lesions.
  • Preoperative tumor spread assessment and monitoring of non-surgical treatments are feasible with OCT, potentially reducing the need for biopsies.
  • Dynamic OCT shows promise in evaluating tumor angiogenesis, wound healing, and laser therapy outcomes.

Conclusions:

  • Optical coherence tomography is a valuable tool for diagnosing epithelial skin tumors in dermatology, improving early detection and treatment planning.
  • OCT can minimize the need for invasive procedures like biopsies by providing detailed preoperative and follow-up information.
  • Dynamic OCT offers new avenues for assessing skin vascularity in conditions like tumors and during therapeutic interventions, including ophthalmological applications for eyelid tumors.