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Updated: Feb 10, 2026

Helical Organization of Blood Coagulation Factor VIII on Lipid Nanotubes
Published on: June 3, 2014
[Successful treatment of acquired hemophilia A with recombinant porcine factor VIII]
K Trautmann-Grill1, O Tiebel2, K Hölig3
1Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus Dresden, Dresden, Deutschland. karolin.trautmann@uniklinikum-dresden.de.
Abstract:
Acquired hemophilia A is a rare, potentially life-threatening disease resulting from autoantibodies against coagulation factor VIII. We report the case of a patient with acquired hemophilia A and severe bleeding after incision of a peritonsillar abscess. Treatment with high dose factor VIII and recombinant activated factor VII failed to control bleeding. However, a single infusion of recombinant porcine factor VIII stopped bleeding efficiently and resulted in measurable factor VIII levels.
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