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SearchGUI: A Highly Adaptable Common Interface for Proteomics Search and de Novo Engines
1Center for Medical Genetics and Molecular Medicine , Haukeland University Hospital , 5021 Bergen , Norway.
Abstract:
Mass-spectrometry-based proteomics has become the standard approach for identifying and quantifying proteins. A vital step consists of analyzing experimentally generated mass spectra to identify the underlying peptide sequences for later mapping to the originating proteins. We here present the latest developments in SearchGUI, a common open-source interface for the most frequently used freely available proteomics search and de novo engines that has evolved into a central component in numerous bioinformatics workflows.
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