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Association of Difference in Coronary Sinus Diameter by Computed Tomographic Angiography Between Patients in and Not
Yancui Li1, Wen Liang2, Jianchun Zhang3
1Department of Radiology, Beijing Luhe Hospital, Capital Medical University, Beijing, China (mainland).
Insights
256-slice coronary computed tomographic angiography effectively measures coronary sinus diameter differences, aiding in the quantification of atherosclerotic plaques. This non-invasive tool offers a feasible approach for evaluating coronary artery anatomy in patients with and without heart failure.
Area of Science:
- Cardiovascular Imaging
- Diagnostic Cardiology
- Medical Technology
Background:
- Current methods for assessing coronary arterial plaque morphology are limited.
- Retrograde cardiac arteriography and magnetic resonance angiography have significant drawbacks.
- There is a need for improved, non-invasive techniques to evaluate coronary artery anatomy.
Purpose of the Study:
- To evaluate the utility of coronary sinus diameter differences in quantifying stable atherosclerotic plaques.
- To utilize 256-slice coronary computed tomographic angiography for this assessment.
Main Methods:
- A cross-sectional study involving 336 patients, divided into heart failure (study group) and non-heart failure (non-study group) cohorts.
- 256-slice coronary computed tomographic angiography with prospective electrocardiogram gating was performed.
- Quantitative measurements of coronary sinus dimensions were analyzed using statistical tests.
Main Results:
- Significant differences in coronary sinus ostium diameters were observed (p<0.0001).
- Coronary sinus size differed significantly between patients with and without heart failure (p<0.0001).
- Patients with heart failure exhibited longer coronary sinuses compared to the non-study group (p<0.0001).
Conclusions:
- 256-slice coronary computed tomographic angiography is a feasible non-invasive tool for evaluating coronary artery anatomy.
- Coronary sinus diameter measurements show potential for quantifying atherosclerotic plaques.
- This technique offers a valuable alternative for cardiac imaging.
Abstract:
BACKGROUND Pathological finding fail to describe the morphology of coronary arterial plaques. Retrograde cardiac arteriography is a complicated procedure and does not detect all left posterior and marginal veins of the heart. Magnetic resonance angiography has long scan time and low spatial resolution. The objective of the present study was to assess the possible utility of the difference in coronary sinus diameter to quantify stable atherosclerotic plaque(s) using 256-slice coronary computed tomographic angiography. MATERIAL AND METHODS A total of 336 patients were divided into 2 groups with 168 patients each. Patients who had heart failure were included in the study group and those who did not were included in the non-study group. Patients were subjected to cross-sectional study. Cardiovascular images were performed with 256-slice coronary computed tomographic angiography with a prospective electrocardiogram and clinical manifestation. Two-tailed paired t test following Dunnett's multiple comparison tests was performed for the quantitative measurement of coronary computed tomographic angiography and clinical manifestation at 99% confidence level. RESULTS The clinical manifestation did not clearly show cardiac abnormality. The diameters of the superoinferior coronary sinus ostium was than that of the anteroposterior coronary sinus ostium, (p<0.0001, q=26.325). There was the difference in size of the coronary sinus ostium between patients in and not in heart failure (p<0.0001). The study group patients had longer coronary sinuses than patients in the non-study group (p<0.0001). CONCLUSIONS 256-slice computed tomographic angiography is a feasible and is non-invasive bio-tool for evaluation of coronary artery anatomy.
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