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Published on: September 15, 2023
Economics of cancer biomarkers
John E Schneider1, Manpreet K Sidhu2, Cynthia Doucet3
1Oxford Outcomes/ICON Plc, 161 Madison Avenue, Suite 205, Morristown, NJ 07960, USA.
Abstract:
Cancer accounts for approximately 13% of all deaths worldwide, and in 2010 the estimated total cost of cancer in the USA was more than US$263 billion. Biomarker use for screening, monitoring, diagnosis and treatment optimization has the potential to improve patient outcomes and reduce costs associated with inappropriate (or suboptimal) therapeutic regimens. Since a new technology may have additional initial cost, a policy question arises regarding whether the improvement in outcomes is attained at a 'reasonable' additional cost compared with existing technology. This paper presents an overview of health economic issues surrounding biomarkers in general, with a focus on cancer care and treatment optimization in particular. While this article is not a systematic review of the literature, it includes relevant examples to provide a real-world perspective.
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