Related Experiment Video
Updated: Feb 10, 2026
Pseudofracture: An Acute Peripheral Tissue Trauma Model
Published on: April 18, 2011
Evaluation of massive transfusion protocol practices by type of trauma at a level I trauma center
Roshan Givergis1, Swapna Munnangi1, Katayoun Fayaz M Fomani2
1Department of Emergency Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Insights
Massive transfusion protocol (MTP) practices differ significantly between penetrating and blunt trauma patients, impacting outcomes. Vigilant, tailored transfusion strategies are crucial for improving trauma patient survival.
Area of Science:
- Trauma Surgery
- Emergency Medicine
- Transfusion Medicine
Background:
- Massive transfusion protocols (MTPs) are critical for managing severe hemorrhage in trauma patients.
- Understanding variations in MTP application based on trauma type is essential for optimizing patient care.
- Level I trauma centers manage a diverse range of traumatic injuries requiring rapid and effective resuscitation.
Purpose of the Study:
- To evaluate and compare massive transfusion protocol practices and outcomes between blunt and penetrating trauma types.
- To identify specific differences in transfusion strategies and patient characteristics based on trauma mechanism.
- To assess the effectiveness of a standardized MTP across different trauma etiologies.
Main Methods:
- Retrospective analysis of 76 trauma patients with MTP activation from March 2010 to January 2015.
- Comparison of patient demographics, transfusion practices, and clinical outcomes stratified by trauma type (blunt vs. penetrating).
- Statistical analysis to determine significant differences in injury severity, survival probability, and treatment modalities.
Main Results:
- Penetrating trauma patients were younger, had lower injury severity scores (ISS), higher probability of survival (POS), and better Glasgow Coma Scale (GCS) scores.
- Head injuries were most common in blunt trauma (36.21%), while abdominal injuries predominated in penetrating trauma (55.56%).
- Penetrating trauma patients received significantly higher plasma content therapy (p < 0.01) despite similar coagulopathy timing.
Conclusions:
- Significant differences in transfusion characteristics and outcomes exist between blunt and penetrating trauma patients, even with a uniform MTP.
- The complexity of implementing MTPs necessitates vigilant and tailored transfusion practices for diverse trauma populations.
- Optimizing MTPs based on trauma type may improve clinical outcomes and reduce mortality in severely injured patients.
Purpose:
To evaluate massive transfusion protocol practices by trauma type at a level I trauma center.
Methods:
A retrospective analysis was performed on a sample of 76 trauma patients with MTP activation between March 2010 and January 2015 at a regional trauma center. Patient demographics, transfusion practices, and clinical outcomes were compared by type of trauma sustained.
Results:
Penetrating trauma patients who required MTP activation were significantly younger, had lower injury severity score (ISS), higher probability of survival (POS), decreased mortality, and higher Glasgow Coma scale (GCS) compared to blunt trauma patients. Overall, the mortality rate was 38.16%. The most common injury sustained among blunt trauma patients was head injury (36.21%), whereas the majority of the penetrating trauma patients sustained abdominal injuries (55.56%). Although the admission coagulation parameters and timing of coagulopathy were not significantly different between the two groups of patients, a significantly higher proportion of penetrating trauma patients received high plasma content therapy relative to blunt trauma patients (p < 0.01).
Conclusion:
Despite the use of the same MTP for all injured patients requiring massive transfusion, significant differences existed between blunt trauma patients and penetrating trauma patients. These differences in transfusion characteristics and outcomes following MTP activation underscore the complexity of implementing MTPs and warrant vigilant transfusion practices to improve outcomes in trauma patients.
More Related Videos
Related Concept Videos
01:15Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
02:45Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
02:33Lattice Centering and Coordination Number
Types of Unit Cells
Imagine taking a large number of identical...
00:58Center of Gravity
01:15Center of Gravity
To determine its location, the principle of moments can be utilized by dividing the object into...
00:59Center of Mass
The knowledge of the center of mass can also help us to describe and predict the motion of objects. For example, when a ball is thrown...