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Updated: Feb 10, 2026

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
Published on: January 31, 2025
Sensitivity analysis of ultrasonic guided waves propagating in trilayered bone models: a numerical study
Tho N H T Tran1, Lawrence H Le2, Mauricio D Sacchi3
1Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, T6G 2B7, Canada.
Abstract:
The fundamental ultrasonic guided modes are consistently observed in long bones ex vivo and in vivo. However, the responses of ultrasonic guided waves to the changes of cortical thickness, cortical elastic parameters, and thickness of the overlying soft tissues are not comprehensively understood. This paper systematically presents a sensitivity analysis of leaky Lamb modes to the geometry and material characteristics of layered bone model by means of semi-analytical finite element modeling. The stratified bone model is consisted of a transversely isotropic cortex with an overlying soft tissue and underlying marrow. The study is important as it offers guidance to the parameter inversion process about the optimal selection of guided modes and regions of sensitivity for better inversion results.
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