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Updated: Feb 10, 2026

Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products
Published on: August 22, 2017
Shortening NMR experimental times
Reika Masuda1, Abhishek Gupta1, Tim Stait-Gardner1
1Nanoscale Organisation and Dynamics Group, Western Sydney University, Penrith, NSW, 2751, Australia.
Abstract:
Conventionally, arrayed nuclear magnetic resonance experiments, such as diffusion and relaxation, are performed with the same number of scans (NS) at each iteration despite the signal-to-noise ratio being more than sufficient for many of the iterations. Here, we propose a simple yet effective approach that significantly shortens experimental times by varying NS through the arrayed experiments while keeping the signal-to-noise ratio essentially the same and retaining experimental accuracy.
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