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Updated: Feb 10, 2026
13:08
Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
Published on: December 2, 2015
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Quantifying fast optical signal and event-related potential relationships during a visual oddball task
Nicole Proulx1, Ali-Akbar Samadani1, Tom Chau1
1Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Road, Toronto, Ontario, M4G 1R8, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario, M5S 3G9, Canada.
Neuroimage
|May 20, 2018
Summary
This study quantifies the relationship between event-related potentials (ERPs) and the fast optical signal (FOS) during a visual task. Findings show spectral coherence between ERPs and FOS DC intensity in some participants, suggesting potential for combined neuroimaging.
Area of Science:
- Neuroscience
- Biomedical Engineering
- Cognitive Science
Background:
- Event-related potentials (ERPs) have validated the fast optical signal (FOS) primarily through temporal correspondence.
- Previous validation methods for FOS have limitations in comprehensively assessing its relationship with ERPs.
- Quantifying electro-optical relationships in both time and frequency domains is crucial for advancing neuroimaging techniques.
Purpose of the Study:
- To systematically quantify the relationship between FOS and ERP responses in time and frequency domains.
- To investigate the spectral coherence and causal influence between FOS and ERPs during a visual oddball task.
- To assess the potential of combined NIRS-EEG for neuroimaging applications.
Main Methods:
- Co-located Near-infrared spectroscopy (NIRS) and electroencephalography (EEG) sensors over the prefrontal cortex.
- Participants performed a visual oddball task with mental counting of oddball stimuli.
- Analysis included time-domain correlations and frequency-domain coherence and Granger causality between FOS and ERP responses.
Main Results:
- A visual oddball task elicited characteristic ERPs (positive at 200 ms, negative at 300-500 ms).
- A decrease in FOS DC intensity was observed 150-250 ms post-stimulus in 10/15 participants.
- Significant spectral coherence (3-5 Hz) and Granger causality (2-6 Hz) between ERP and FOS were found in subsets of participants, despite low FOS signal-to-noise ratio.
Conclusions:
- The ERP and FOS DC intensity signal exhibit spectral coherence in specific frequency bands related to prefrontal cortex activity.
- These electro-optical relationships are present in a subset of individuals, highlighting variability in signal quality.
- Further research is needed to improve FOS signal quality for practical applications like brain-computer interfaces.
Keywords:
Electroencephalography (EEG)Event-related potentialFast optical signalNear-infrared spectroscopy (NIRS)Prefrontal cortexVisual oddball paradigmMore Related Videos
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