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Primary lymphoma of appendix presenting as acute appendicitis: A case report
Giuseppe Caristo1, Guido Griseri1, Rosario Fornaro2
1San Paolo Hospital, Via Genova 30, Savona, 17100, Italy.
International Journal of Surgery Case Reports
|May 20, 2018
Summary
Primary appendiceal lymphoma, a rare gastrointestinal malignancy, often mimics acute appendicitis. Surgical resection and chemotherapy are effective, highlighting the importance of histopathological examination of all appendectomies.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Primary lymphomas of the appendix are exceptionally rare, accounting for only 0.015% of all gastrointestinal lymphomas.
- Appendiceal neoplasms frequently present with symptoms of acute appendicitis due to luminal obstruction.
Purpose of the Study:
- To report a case of primary appendiceal lymphoma.
- To emphasize the diagnostic challenges and treatment efficacy.
Main Methods:
- A case presentation of a 75-year-old male with right lower quadrant abdominal pain and fever.
- Laparotomic appendectomy followed by histopathological examination.
Main Results:
- Histopathology confirmed diffuse large B-cell lymphoma of the appendix.
- Preoperative diagnosis of appendiceal lymphoma is challenging, often relying on post-operative histopathology.
Conclusions:
- Primary appendiceal lymphoma is a rare entity with no established therapeutic guidelines.
- Surgical resection combined with adjuvant chemotherapy demonstrates high efficacy.
- Mandatory histopathological examination of all appendectomy specimens is crucial for diagnosis.
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